Balding man.

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Comprehensive Transcriptome Profiling of Balding and Non-Balding Scalps in Trichorhinophalangeal Syndrome Type I Patient

BACKGROUND Trichorhinophalangeal syndrome (TRPS) patients tend to have alopecia that appears to be androgenetic, and this genetic model might give clues to the pathogenesis of hair loss or hair morphogenesis. OBJECTIVE This study was conducted to identify additional genetic evidence of TRPS and hair morphogenesis from a TRPS patient. METHODS From one TRPS type I patient, we extracted RNA an...

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Balding hair follicle dermal papilla cells contain higher levels of androgen receptors than those from non-balding scalp.

Androgens can gradually transform large scalp hair follicles to smaller vellus ones, causing balding. The mechanisms involved are unclear, although androgens are believed to act on the epithelial hair follicle via the mesenchyme-derived dermal papilla. This study investigates whether the levels and type of androgen receptors in primary lines of cultured dermal papilla cells derived from balding...

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Fitting the Balding-Nichols model to forensic databases.

Large forensic databases provide an opportunity to compare observed empirical rates of genotype matching with those expected under forensic genetic models. A number of researchers have taken advantage of this opportunity to validate some forensic genetic approaches, particularly to ensure that estimated rates of genotype matching between unrelated individuals are indeed slight overestimates of ...

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Validity of self reported male balding patterns in epidemiological studies

BACKGROUND Several studies have investigated the association between male pattern baldness and disease such as prostate cancer and cardiovascular disease. Limitations in the lack of standardized instruments to measure male pattern baldness have resulted in researchers measuring balding patterns in a variety of ways. This paper examines the accuracy and reliability of assessment of balding patte...

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Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3.

BACKGROUND A recent report suggested that men with vertex balding have higher levels of plasma insulin-like growth factor 1 (IGF-1). The association of its major carrier protein, insulin-like growth factor binding protein 3 (IGFBP-3), with male pattern hair loss has not been examined. OBJECTIVE We evaluated the relations of plasma concentrations of IGF-1 and IGFBP-3 with vertex balding in mid...

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ژورنال

عنوان ژورنال: BMJ

سال: 1972

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.3.5820.234-a